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 ONE HEALTH / Noncommunicable chronic diseases / Metabolic diseases

Laboratory of biochemistry and biology of nuclear lipids

Study of the composition, organization, dynamics, and homeostasis
of nuclear lipid droplet populations

Work team

Principal InvestigatorVes Losada

Ves Losada, Ana

Investigator
avlosada@biol.unlp.edu.ar

Girotti, Juan RobertoGirotti J.

Investigator
jgirotti@med.unlp.edu.ar

Collaborators from other institutions

Dr. Favale, Nicolás Octavio
Cátedra de Biología Celular y Molecular, FFYB-UBA-IQUIFIB-CONICET

Line overview

Study of the composition, organization, dynamics and homeostasis of the population of Nuclear Lipid Droplets.

“Nuclear lipid droplets proteome: carboxylesterase as a nuclear lipase involved in lipid-droplet homeostasis”
Lagrutta Lucía C; Layerenza Juan P;Bronsoms Silvia; Trejo Sebastián A; Ves-Losada Ana.
2021. Heliyon (2021) 7: e06539
doi.org/10.1016/j.heliyon.2021.e06539

Inhibition of Mevalonate Pathway and Synthesis of the Storage Lipids in Human Liver-Derived and Non-liver Cell Lines by Lippia alba Essential Oils.
Montero-Villegas, S; Polo, M; Galle, M; Rodenak-Kladniew, B; Castro, M; Ves-Losada, A; de Bravo, M. G.
2017. Lipids, 52(1), 37-49

Sistematización y análisis de las innovaciones didácticas en el curso de Biología General de la Facultad de Ciencias Exactas (UNLP).
Pardo, F. M; Petrucci, D; Ves Losada, A.
2017. Trayectorias universitarias. La Plata: Revista de la Dirección de Capacitación y Docencia y la Especialización en Docencia Universitaria dependiente de la Secretaría de Asuntos Académicos de la UNLP. vol. 3, n° 5, p. 39-45. ISSN 2469-0090

Reversible Nuclear-Lipid-Droplet Morphology Induced by Oleic Acid: A Link to Cellular-Lipid Metabolism.
Lagrutta, L. C; Montero Villegas, S; Layerenza, J. P; Sisti, M. S; García De Bravo, M.; Ves-Losada, A.
2017. Plos one. San Francisco: PUBLIC LIBRARY SCIENCE, 2017 - p. 1-25. ISSN 1932-6203

Nuclear lipid droplets: a novel nuclear domain.
Layerenza, J. P; González, P; García de Bravo, M; Polo, M; Sisti, M. S; Ves-Losada, A.
2013. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids. Amsterdam: ELSEVIER SCIENCE BV, 2013 - vol. 1831, p. 327-340. ISSN 1388-1981

Metabolismo lipídico en el núcleo celular. Arachidonic acid pools of rat kidney cell nuclei.
Maté, S. M; Layerenza, J. P; Ves-Losada, A.
2011. Mol Cell Biochem. Ed. Kluwer Acad. Publishers.

In vitro antitumor activity of N-glycosyl sulfonamides.
Crespo, R; García de Bravo, M; Colinas, P. A; Bravo, R. D.
2010. Bioorganic & medicinal chemistry letters. Pergamon-Elsevier Science Ltd. vol. 20, p. 6469-6471

Incorporation of arachidonic and stearic acids bound to L-FABP into nuclear and endonuclear lipids from rat liver cells.
Maté, S; Layerenza, J. P; Ves-Losada, A.
2007. Lipids. AOCS Press Springer. vol. 42, p. 589-602



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