Biochemistry of insects and fungal pathogens 
Application topest control


Team of work

Juárez, Marta Patricia
Principal Investigator
mjuarez@isis.unlp.edu.ar
Pedrini, Nicolás
Investigator
nicopedrini@yahoo.com
Calderón Fernández, Gustavo Mario
Investigator
guscalf@gmail.com
Girotti, Juan Roberto 
Investigator
juangirotti@yahoo.com.ar
Dulbecco, Andrea
Research Fellow
andredul87@hotmail.com
Huarte Bonnet, Carla
Research Fellow
carlahb@hotmail.es
Moriconi, Débora 
Research Fellow
debomoriconi@hotmail.com
Santos da Paixão, Flavia Reginas
Research Fellow
flaviareginasp@hotmail.com
 Mannino, Constanza
Research Fellow
 constanza.mannino@gmail.com
Davyt, Belén
Research Fellow
bdavyt@gmail.com
Bozzolo, Facundo Oscar
Support Staff
facubozzolo@hotmail.com
Mijailovsky, Sergio
Support Staff
sergiojmi@gmail.com


Collaborators from other institutions

International

Abreo, Eduardo
Instituto Nacional de Investigación Agropecuaria (INIA) Las Brujas, Canelones, Uruguay.

Fernandes, Éverton K.K.
Instituto de Patología Tropical y Salud  Pública (IPTSP), Universidad Federal de Goiás, Brasil.

Gondim, Katia
Instituto de Bioquímica Médica, Universidad Federal de Rio de Janeiro, Rio de Janeiro, Brasil.

Luz, Christian
Instituto de Patología Tropical y Salud  Pública, Universidad Federal de Goiás, Brasil.

Rangel; Drauzio E.N.
Instituto de Patología Tropical y Salud  Pública, Universidad Federal de Goiás, Brasil.

Ranson, Hilary
Departamento de Biología de Vectores, Escuela de Medicina Tropical de Liverpool, Liverpool, Reino Unido.

Vontas, John

Instituto de Biología Molecular y Biotecnología, Heraklion, Grecia.


National

Cardozo, Rubén M.
Instituto de Patología Experimental, Facultad de Ciencias de la Salud, Universidad Nacional de Salta, Salta.

Gentile, Alberto
Ministerio de Salud Pública, Salta. Provincia de Salta. Argentina.

Lori, Gladys A.
Instituto de Fisiología Vegetal, Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, La Plata. Provincia de Buenos Aires. Argentina

Padín, Susana B.
Cátedra de Terapéutica Vegetal, Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, La Plata. Provincia de Buenos Aires. Argentina.

Rabinovich, Jorge
Centro de Estudios Parasitológicos y de Vectores, La Plata. Provincia de Buenos Aires. Argentina.




Line overview

Studies on the biochemistry and molecular biology of insects and pathogenic fungi are carried out at the Laboratory of Insect Biochemistry. They are of interest to sanitary conditions and agriculture.
Our goal is to get further knowledge in the biochemical processes of these organisms for developing new methodologies in the control of plagues.

Insects

Our interest is centered on the composition, structure, metabolism and function of lipids and cuticular pheromones of these insects, cuticular hydrocarbons in triatominae as a useful tool in chemical taxonomy and their role in resistance to pyrethroids. New tools of low environmental impact will be developed for the control of plagues. Epidemiologically important insects are triatominae (Hemiptera, Reduviidae), vectors of Chagas disease (Triatoma infestans, T. dimidiata, T. sordida and Rhodnius prolixus). Among insects affecting agro-derived products, we will study the pest of stored grain beetles (Tribolium castaneum, Sitophilus oryzae, Rizopertha dominica, Ulomoides dermestoides, Acanthoscelides obtectus).

Entomopathogenic fungi

Cuticle of insects was found to be the new target for their control. Biochemical and biological interactions of entomopathogenic fungi (Beauveria bassiana) and their host will be studied. These studies have been focused on the metabolic pathway on the insect lipid degradation by entomopathogenic fungi.

Insect-fungus interactions and the insect behavior were studied in order to develop an “attraction-infection” trap for controlling sucking bugs. This study was based on entomopathogenic fungi and contact pheromones, and it proved to be successful not only in the laboratory but also in field assays. We are currently studying the effect of bioinsecticide on the insect population dynamics and reduction of infection risk with the parasite.

Phytopathogenic fungi

The presence of toxigenic fungi in wheat and other cereals causes important sanitary and economical problems. The pathogenic fungus Fusarium graminearum produces the wheat ear disease, contaminating cultures and their derivatives with toxins from the trichothecene group, mainly deoxynivalenol (DON) and other derivatives. Also, volatile metabolites of Fusarium sp. were characterized, evidencing their use as taxonomic markers. Novel approaches for the early detection of contamination in mycotoxin-producing fungi in culture, were designed.

 

Publications

 

  • Cytochrome P450associated with insecticide resistance catalyzes cuticular hydrocarbonproduction in Anopheles gambiae.
    Balabanidou, V; Kampouraki, A; Mac Lean, M; Blomquist, G. J; Tittiger, C; Juárez, M. P; Mijailovski, S. J.
    2016.
    Proceedings of the National Academy of Sciences of the United States of America. Washington DC, USA: NATL ACAD SCIENCES, vol. 113, ISSN 0027-8424
  • Lipid Metabolismin Rhodnius Prolixus: Lessons from the genome.
    Majerowicz, D; Calderón Fernández, G. M; Alves Bezerra, M; De Paula, I; Cardoso, L. S; Juárez, M. P; Atella, G. C; Gondim, K. C.
    2016. Gene, Amsterdam: ELSEVIER SCIENCE BV, vol. 596, p. 27-44.
    ISSN 0378-1119
  • Rhodniusprolixus supergene families of enzymes potentially associated with insecticide resistance.
    Schama, R; Pedrini, N; Juárez, M. P; Nelson, D. R; Torres, A. Q; Valle. D; Mesquita, R. D.
    2016. Insect biochemistry andmolecular biology. Amsterdam: Pergamon-Elsevier Science Ltd, vol. 69, p. 91-104. ISSN 0965-1748
  • Assessing gene expression during pathogenesis: Use of qRT-PCR to 4 follow toxin production in the entomopathogenic fungus Beauveria 5 bassiana during infection and immune response of the insect host 6 Triatoma infestans.
    Lobo, L; Luz, C; Fernandez, E.  K; Juárez, M. P; Pedrini, N.
    2015.
    Journal of Invertebrate Pathology. , Amsterdam: ACADEMIC PRESS INC ELSEVIER SCIENCE, vol. 128, p. 14-21. ISSN 0022-2011

  • Biological control of the Chagas disease vector Triatoma infestans with the entomopathogenic fungus Beauveria bassiana combined with an aggregation cue: field, laboratory and mathematical modeling assessment.
    Forlani, L; Pedrini, N; Girotti, J. R; Mijailovski, S. J; Gentile, A; Cardozo, R. M; Hernández-Suarez, C; Rabinovich, J; Juárez M. P.
    2015. Plos Neglected Tropical Diseases. , San Francisco: PUBLIC LIBRARY SCIENCE, vol. 13, n° 5, p. 1
    -23. ISSN 1935-2735

  • Deltamethrin Binding to Triatoma infestans (Hemiptera: Reduviidae) Lipoproteins. Analysis by Solvent Bar Microextraction Coupled to Gas Chromatography.
    Dulbecco, A. B; Mijailovsky, S. J; Girotti, J. R; Juárez, M. P.
    2015. Journal of Medical Entomology. , Lanham: ENTOMOLOGICAL SOC AMER. ISSN 0022-2585


  • Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection.
    Mesquita, R; Vionette-Amaral, R; Lowenberger, C; Rivera-Pomar, R; Monteiro, F; Minx, P; Spieth, J; De Carvalho, B; Panzera, F; Lawson, D; Torres, A; Ribeiro, J; Sorgine, M; Waterhouse, R; Montague, M; Abad-Franch, F; Alves-Becerra, M; Amaral, L; Araujo, H; Araujo, R; Calderón-Fernandez, G; Carareto, C; Christensen, M; Costa, I; Costa, S; Dansa, M; Daumas-Filho, C; De Paula, I; Dias, F; Dimopoulos, G; Emrich, S; Esponda Behrens, N; Fampa, P; Fernández Medina, R; Fonseca, R; Fontenele, M; Fronik, C; Fulton, L; Gandara, A; García, E; Genta, F; Giraldo-Calderón, G; Bruno Gomes, K; Gondim, A; Granzotto, A; Aparecida Guarneri, Roderic Guigó, Harry, M; Hughes, D; Jablonka, W; Jacquin-Joly, E; Juárez, M. P; Koerich, L; Latorre-Estivalis, J; Lavore, A; Lawrence, G; Lazosk, C; Lazzari, C. R; Lopes, R; Lorenzo, M; Lugon, M; Majerowicz, D; Marcet, P. L; Mariotti, M; Hatisaburo Masuda, Megy, K; Melo, A; Missirlis, F; Theo P. Mota, Noriega, F. G; Nouzova, M; Nunes, R. D; Oliveira, R. L. L; Oliveira-Silveira, G; Ons, S; Pagola, L; Paiva-Silva, G. O; Pascual, A; Pavan, M. G; Pedrini, N; Peixoto, A. A; Pereira, M. H; Pike, A; Polycarpo, C; Prosdocimi, F; Ribeiro-Rodrigues, R; Robertson, H. M; Salerno, A. P; Salmon, D; Santesmasses, D; Schama, R; Eloy S. Seabra-Junior, Silva-Cardoso, L; Silvaneto, M. A. C; Souza-Gomes, M; Sterkel, M; Taracena, M. L; Tojo, M; Zhijian Jake Tu; Tubio, J. M. C; Ursic-Bedoya, R; Venancio, T. M; Walter-Nuno, A. B; Wilson, D; Warren, W. C; Wilson, R. K; Huebner, E; Dotson, E; Oliveira, P. L.
    2015.
    Proceedings of The National Academy of Sciences of The United States of America., Washington DC, USA: NATL ACAD SCIENCES, vol. 112, p. 14936
    -14941. ISSN 0027-8424

  • Genomic and functional characterization of a methoprene-tolerant gene in the kissing-bug Rhodnius prolixus.
    Villalobos-Sambucaro, M. J; Riccillo, F. L; Calderón Fernández, G. M; Sterkel, M; Diambra, L; Ronderos, J. R.
    2015. General and Comparative Endocrinology. Amsterdam: ACADEMIC PRESS INC ELSEVIER SCIENCE, vol. 216, p. 1-8. ISSN 0016-6480

  • Tenebrionid secretions and a fungal benzoquinone oxidoreductase form competing components of an arms race between a host and pathogen.
    Pedrini, N; Ortiz-Urquiza, A; Huarte Bonnet, C; Fan, Y; Juárez, M. P; Keyhani Nemat, O.
    2015. Proceedings of the National Academy of Sciences of The United States of America. , Washington DC, USA: NATL ACAD SCIENCES, vol. 112, n° 28, p. 3651-3660. ISSN 0027-8424

  • Unveiling chemical defense in the rice stalk stink bug against the entomopathogenic fungus Metarhizium anisopliae.
    Silva, R. A; Quintela, E. D; Mascarin, G. M; Pedrini, N; Lião, L. M; Ferri, P. H.
    2015. Journal of Invertebrate Pathology. : ACADEMIC PRESS INC ELSEVIER SCIENCE, vol. 127, p. 93-100. ISSN 0022-2011
  • Oxidative stress in entomopathogenic fungi grown on insect-like hydrocarbons. 
    Huarte Bonnet, C; Juárez, M. P; Pedrini, N . 
    2014. Current Genetics. , Berlin: SPRINGER,. ISSN 0172-8083


  • Toxicological and biochemical response of the entomopathogenic fungus Beauveria bassiana after exposure to deltamethrin. 
    Forlani, L; Juarez, M. P; Lavarias, S; Pedrini, N. 
    2014. Pest Management Science. , Londres: JOHN WILEY & SONS LTD,. vol. 70, p. 751-756. ISSN 1526-498X


  • Toxigenic Capacity and Trichothecene Production by Fusarium graminearum Isolates from Argentina and Their Relationship with Aggressiveness and Fungal Expansion in the Wheat Spike. 
    Malbrán, I; Mourelos, C. A; Girotti, J. R; Lori, G. A; Balatti, P. A. 
    2014. Crop Protection. , Amsterdam: ELSEVIER SCI LTD,. vol. 104, n° 4, p. 357-364. ISSN 0261-2194


  • Cuticular hydrocarbons of the Triatoma sordida species subcomplex (Hemiptera: Reduviidae).
    Calderón Fernández, G. M; Juárez, M. P. 
    2013. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro: Fundaco Oswaldo Cruz, vol. 108, p. 778-784. ISSN 0074-0276

  • Análisis de la expresión de genes de hongos entomopatógenos mediante RT-PCR. 
    Pedrini, N; Berón, C; Consolo, V, F. 
    2013. Mar del Plata: Universidad Nacional de Mar del Plata, p. 43-49. ISBN 978-987-544-530-7
  • Evaluación de la actividad insecticida de tierras de diatomeas de yacimientos argentinos.
    Fusé, C. B; Villaverde, M. L; Padin, S. B; De Giusto, M; Juárez, M. P. 
    2013. Revista RIA. INTA. Ministerio de Agricultura, Ganadería y Pesca de la Nación. vol. 39, n° 2, p. 207-213. ISSN 0325-8718
  • In vitro comparative analysis of antiproliferative activity of essential oil from mandarin peel and its principal component limonene
    Manassero, C; Girotti, J. R; Mijailovsky, S; García de Bravo, M; Polo, M. 
    2013. Natural Product Research. Londres: Taylor & Francis LTD, 2013 - . vol. 27, p. 1475-1478. ISSN 1478-6419
  • Targeting of insect epicuticular lipids by entomopathogenic fungi: hydrocarbon oxidation within the context of a hostpathogen interaction. 
    Pedrini, N; Ortiz-Urquiza, A; Huarte Bonnet, C; Zhang, S; Keyhani, N. O.
    2013. Frontiers in Microbiology. Lausana: Frontiers, 2013 - . p. 4-24. ISSN 1664-302X
  • Toxicity and repellency of nine medicinal plants against Tribolium castaneum in stored wheat. 
    Padín, S. B; Fusé, C. B; Urrutia, M. I; Dal Bello, G. M.
    2013. Bulletin of Insectology. , Bologna: Alma Mater Studiorum, Univ Bologna. vol. 66, p. 45-49. ISSN 1721-8861
  • Aggressiveness variation of Fusarium graminearum isolates from Argentina following point inoculation of field grown wheat spikes.
    Malbrán, I; Mourelos, C. A; Girotti, J. R; Aulicino, M. B; Balatti, P. A; Alori, G.
    2012. Crop protection. , Amsterdam: ElSevier SCI Ltd, vol. 42, p. 234-243


  • Cuticular hydrocarbon pattern as a chemotaxonomy marker to assess intraspecific varibility in Triatoma infestans, a major vector of Chagas' disease. 
    Calderón Fernández, G; Girotti, J. R; Juárez, M. P.  
    2012. Medical and Veterinary Entomology. , London: Wiley-Blackwell Publishing, INC. vol. 26, p. 201-209


  • CYP52X1, representing a new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in the entomopathogenic fungus Beauveria Bassiana.
    Shizhu Zhang; Widemann, E; Bernard, G; Lesot, A; Pinot, F; Pedrini, N; Keyhani, T. O.
    2012. Journal of biological chemistry., Bethesda, Maryland: Amer Soc Biochemistry Molecular Biology Inc, vol. 287, n° 16, p. 13477-13486


  • Early detection of toxigenic Fusarium graminearum in wheat.
    Girotti, J. R; Malbrán, I; Lori, G; Juárez, M. P.
    2012. World Mycotoxin Journal., Wageningen:Wageningen Academic Publishers, vol. 5, p. 143-152. ISSN 1875-0710


  • Epicuticular hydrocarbons of the sugarcane borer Diatraea saccharalis (Lepidoptera: Crambidae). 
    Girotti, J. R; Mijailovsky, S. J; Juárez, M. P.
    2012. Physiological entomology (online) , Londres: Wiley-Blackwell Publishing, Inc. vol. 37, n° 3, p. 266-277. ISSN 1365-3032


  • Cuticular Hydrocarbons of Triatoma dimidiata (Hemiptera: Reduviidae): Intraspecific Variation and Chemotaxonomy. 
    Calderón-Fernández, G. M; Girotti, J. R; Juárez, M. P.
    2011. Journal Medical Entomology 48 (2): 262-271
    Editorial: Entomological Society of America. 

  • Epicuticle Lipids Mediate Mate Recognition in Triatoma infestans. 
    Cocchiararo-Bastias, L. M; Mijailovsky, S. J; Calderon-Fernández, G M;  Lorenzo Figueiras, A. N; Juárez, M. P.
    2011. Journal of Chemical Ecology 37(3): 246–252
    Editorial: Springer. 

  • Capacidad insecticida de Beauveria bassiana cultivada en hidrocarburos para el control de coleópteros en granos almacenados.
    Pedrini, N; Dal Bello, G; Padín, S.B; Juárez, M. P.
    2011. Agrociencia (Uruguay) 15(1): 64-69


  • Insecticidal effect of fenitrothion, diatomaceous earth and Beauveria bassiana against Coleopteran pests on stored grain.
    Dal Bello, G; Fusé, C; Juárez, M. P; Pedrini, N; Imaz, A; Padín, S. 
    2011. Integrated Protection of Stored Products. IOBC/wprs Bulletin Editorial: International Organization of Biological Control.

  • Cytotoxic and genotoxic effects of defence secretion of Ulomoides dermestoides on A549 cells. 
    Crespo, R; Villaverde, M. L; Girotti, J. R; Guerci, A; Juárez, M. P; García de Bravo, M. 
    2011. Ethnopharmacology, 136: 204-209


  • The cuticular hydrocarbon pattern as chemotaxonomy marker to assess the intraspecific varibility in Triatoma infestans, a major Chagas disease vector. 
    Calderón-Fernández, G. M; Girotti, J. R; Juárez, M. P.
    2011. Medical and Veterinary Entomology 2: 135-140


  • Contribution of the horizontal transmission of the entomopathogenic fungus Beauveria bassiana to the overall performance of a fungal powder formulation against Triatoma infestans. 
    Forlani, L; Pedrini, N; Juárez, M.P.
    2011. Research and Report in Tropical Medicine 2, 135-140


  • Beauveria bassiana infection alters colony development and defensive secretions of the beetles Tribolium castaneum and Ulomoides dermestoides (Coleoptera: Tenebrionidae)
    Pedrini, N; Villaverde, M. L; Fusé, C. B; Dal Bello, G. M; Juárez, M. P.
    2010. Journal of Economic Entomology. Entomological Soc Amer.
     vol. 103, n° 4, p. 1094-1099

  • Cuticular hydrocarbons of Triatoma dimidiata (Hemiptera: Reduviidae): intraspecific variation and chemotaxonomy
    Calderón Fernández, G.M; Girotti, J. R; Juárez, M. P.
    2010
    . Landham, Maryland. Journal of Medical Entomology; vol. 48 p. 262 - 271
  • Molecular characterization and expression analysis of a suite of cytochrome P450 enzymes implicated in insect hydrocarbon degradation in the entomopathogenic fungus Beauveria bassiana. 
    Pedrini, N; Zhang, S; Juárez, M. P; Keyhani. N. O. 
    2010Microbiology-uk. Soc. General Microbiology. vol. 156, p. 2549-2557
  • Use of solid phase microextraction coupled to capillary gas chromatography-mass spectrometry for screening Fusarium spp. based on their volatile sesquiterpenes. 
    Girotti, J. R; Malbrán, I; Lori, G; Juarez, M .P. 
    2010. World Mycotoxin Journal. Wageningen, The Netherlands: Wageningen Academic Publishers. vol. 3, n° 2, p. 121-128. ISSN 1875-0710

  • Epicuticular lipids induce aggregation in Chagas disease vectors. 
    Figueiras, L. A. N; Girotti, J. R; Mijailovsky, S. J; Juárez, M. P.  
    2009. Parasite and Vectors. Londres. BioMed Central Ltd, vol. 2, p. 1-7. ISSN 1756-3305
  • Control of pyrethroid-resistant Chagas disease vectors with entomopathogenic fungi. 
    Pedrini, N; Mijailovsky, S; Girotti, J; Stariolo, R; Cardozo R; Gentile, A; Juárez, M. P. 
    2009. PLoS Neglected Tropical Diseases. Public Library of Science, vol. 3, n° 481, p. 1-10. ISSN 1935-2727
  • Volatile secretions and epicuticular hydrocarbons of the beetle Ulomoides dermestoides. 
    Villaverde, M. L; Girotti, J.R; Mijailovsky, S; Pedrini, N; Juárez, M. P. 
    2009. Comparative Biochemistry and Physiology. part b, Biochemistry & Molecular Biology. Elsevier Science Inc, vol. 154, p. 381-386 

  • Volatile organic compounds released by the entomopathogenic fungus Beauveria bassiana.
    Crespo, R; Pedrini, N; Juárez, M. P; Dal Bello, G. 
    2008. Microbiological Research. Elsevier, vol. 163, p. 148-151 

  • Biochemistry of the insect epicuticle degradation by entomopathogenic fungi. 
    Pedrini, N; Juárez, M. P; Crespo, R. 
    2007. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. Nueva York: Elsevier. vol. 146C, n° 2, p. 124-137
  • Cuticular hydrocarbons of triatomines. 
    Juárez, M. P; Calderón Fernández, G.
    2007. Nueva York: Elsevier. Comparative Biochemistry and Physiology a Molecular and Integrative Physiology.vol. 147, p. 711-730
  • Detection of Tribolium castaneum (Herbst) volatile defensive secretions by solid phase microextraction capillary gas chromatography (SPME-CGC) analysis.
    Villaverde, M. L; Juárez, M. P; Mijailovsky, S.
    2007. Journal of Stored Products Research. Jena: Elsevier. vol. 43, p. 540-545



Book - Book chapters

  • Pyrethroid Resistance in Chagas Disease Vectors: The case of Triatoma infestans cuticle. 
    Juárez, M. P; Pedrini, N; Girotti, J. R; Mijailovsky, S. 
    2010. Review. Resistance Pest Management.; M. P. Juarez, N. Pedrini, J. R. Girotti and S. J. Mijailovsky: Center for Integrated Plant Systems (CIPS) in Cooperation with the Insecticide Resistance Action Committee (IRAC). p. 59-61
  • Hidrocarburos cuticulares de triatominos. 
    Juárez, M.P, Calderón Fernández, G, Mijailovsky, S; Girotti, J, Macedo López, C
    2008. Triatominos de Bolivia. Cochabamba, Bolivia: Ministerio de Salud y Deportes de Bolivia, p. 191-201
  • Entomopathogenic fungi and their host cuticle. 
    Pedrini, N; Juárez, M. P. 
    2008. Encyclopedia of Entomology (2nd. Edition). Heidelberg: Springer, p. 1333-1336. ISBN 978-1-4020-6242-1

  • Hidrocarburos epicuticulares de Triatoma: su utilidad en taxonomía química.
    Juárez, M. P; Calderón Fernández, G; Girotti, J; Mijailovsky, S. 
    2007. Taller del Cono Sur. Actualización de la Tripanosomiasis Americana. Asunción, Paraguay: Universidad Nacional de Asunción, Paraguay. p. 97-10

Intellectual property right (in process)

  • Método para la detección temprana de infecciones fúngicas en plantas cultivables, método para evaluar la efectividad de un tratamiento antifúngico y procedimientos.
    Juárez M. P, Girotti, J. R, Lori, G, Malbran, I. 
    2008. Argentina. 11/11/2008. sol. n°:P080104942 Patente de invención. 
    Desarrollo de un Método. Química. Producción vegetal-Cereales
    .
  • Trampa para insectos hematófagos, método de control y método de detección de dichos insectos. 
    Juárez, M. P; Pedrini, N; Girotti, J. R; Mijailovsky, S.; Lorenzo Figueiras, A.
    2008. Argentina. 30/05/2008. sol.n°: P-08102268. Patente de invención. Bien de consumo final o su/s componente/s. Biológica. Enf. Endémicas-Mal de Chagas.

Patents

  • Composición de efecto insecticida, método de aplicación. 
    Juárez M. P. 
    Patente Argentina # 24980. 1996.
  • Trampa para insectos hematófagos, método de control y método de detección de dichos insectos.     
    Juárez,  M. P; Pedrini, N; Girotti, J. R; Mijailovsky, S; Lorenzo Figueiras, A. 
    Solicitud de Patente P 080102268 (presentada ante el INPI, 2008).
  • Método para la detección temprana de infecciones fúngicas en plantas cultivables, método para evaluar la efectividad de un tratamiento antifúngico y procedimientos.
    Girotti, J. R; Lori, G; Malbran, I. I; Juárez, M. P. 
    Solicitud Patente P080104942 (presentada ante el INPI, 2008).

Awards

  • “Premio Bernardo Houssay” 
    Centro de Estudios de la Industria Químico- Farmacéutica (CEDIQUIFA), 2006. Otrogado a la Dra. Juárez, M. Patricia.

  • “Chris J. Lomer Memorial Award”
    Society for Invertebrate Pathology. 
    Otorgado al Dr. Pedrini, Nicolás. 2008

  • “Premio Innovar”
    Categoría Innovaciones en el Agro. “Detección temprana de fusariosis”. 
    Girotti, Juan R; Juárez, M. Patricia; Malbrán, Ismael; Lori, Gladys A.
    Proyecto Nº 3776. 2009. Ministerio de Ciencia, Tecnología e Innovación Productiva, República Argentina.

  • “Preseleccionado para el premio Innovar”
    Categoría Investigación Aplicada. “Trampa para el control de vinchucas”. 
    Juárez, M. P; Pedrini, N; Girotti, J. R; Mijailovsky, S.
    2009. Ministerio de Ciencia, Tecnología e Innovación Productiva, República Argentina.

  • "Premio de la Asociación Latino Americana de Ecología Química" 2010
    Fusarium Head Blight: Chemical signals of early infection. 
    Girotti, Juan; Malbrán, Ismael; Lori, Gladys; Juárez, M. Patricia.





INIBIOLP - Instituto de Investigaciones Bioquímicas de La Plata "Profesor Doctor Rodolfo R. Brenner"
Consejo Nacional de Investigaciones Científicas y Técnicas - Facultad de Ciencias Médicas - U.N.L.P.
Avenida 60 y 120 - C.P. 1900 La Plata - Prov. de Buenos Aires - Argentina. Tel. 54-221-4824894 - Fax. 54-221-4258988 - E-mail :